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Follow the cutting edge
Some of the most exciting innovation taking place in wound healing today is in the area of nanotechnology—the science of making things really, really, really small so they are more likely to get to where they need to go, which in this case is a wound. “Nano-wound care includes nano-silver dressings are really good are killing off scary bacteria, fungi, and viruses,” says Dr. Friedman. (Some bandages and creams already use silver to help reduce bacteria in wounds and cuts, including Curad’s Germ Shield.)
Another huge step will be the advancement of nitric oxide-generating nanoparticles. “Nitric oxide is involved in every step of the wound healing process and in many chronic wounds, nitric oxide production is damaged,” Dr. Friedman says. Nanotechnology that facilitates the production of nitric oxide from its precursor nitrite is in the works.
There’s more: Curcumin—the yellow polyphenol that gives turmeric its brilliant orange color—has been used to heal wounds for centuries, but it turns everything orange if applied topically. But “when you shrink down something in size, we can make orange/yellow curcumin invisible, thereby enabling its use,” he says. “We showed that nano-curcumin can accelerate wound healing in both burn wounds and MRSA-infected wounds.” Stay tuned.
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Tap into PRP
You’re probably doing everything you can to keep your bones healthy, right? What if you could heal a broken one faster? There’s a whole lot of buzz about the use of platelet-rich plasma (PRP) to heal injured tendons, ligaments, muscles, bones and joints, says Allan Mishra, MD, an orthopedic surgeon at Stanford Medical Center in Menlo Park, California. “It is becoming much more mainstream to consider using components of your own blood or bone marrow to treat a host of conditions. The power to heal comes from within.” PRP therapy involves taking some blood (about as much as would be drawn for a cholesterol screen), spinning it to isolate the plasma and all of the growth factors and proteins it contains, and then re-injecting it to the injured area. This can also be done with surgery to accelerate healing and decrease complications. “First and foremost, it is safe as we are using your own blood.” Still, more research is needed to identify ideal formulations for specific injuries, and this work will also encourage insurers to cover the cost of the therapy, which can be high. This evolving field of medicine is called regenerative medicine, and PRP is likely just the tip of the iceberg, he says. “Researchers including those at Replicel are actively trying to isolate the most important growth factors in the blood that can trigger and sustain and healing process.”
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Take on scars
Sometimes the wound repair process ends with a scar, but that doesn’t mean you have to accept this outcome. “A scar may be itchy or painful, have discoloration, redness, textural changes—such as excessive thickening, depression, or ‘railroad track’ marks,” explains Estee Williams, MD, a board-certified dermatologist at Madfes Aesthetic in New York City. “Laser therapy is used to address each of these issues and is extremely important when optimizing the outcome of any scar, be it from trauma, surgery, or a burn.” For example, if the scar is from surgery, a vascular laser such as the Lumenis IPL (intense pulsed light) will selectively target the red part. “It is desirable to treat scars with lasers at this early point, not only for cosmetic reasons but also to facilitate proper wound healing. “By clamping down on the blood vessels ‘feeding’ the scar, IPL has the ability to prevent overgrowth of scar tissue. I recommend continuing monthly treatments until the redness has faded.” Some topical products such as Mederma Advanced Scar Gel or the Biocorneum line of products can also help.